A tiny RNA molecule plays a big role in the development of two diseases affecting billions of people worldwide: heart disease and obesity. Yale researchers have found that by disrupting this microRNA in key tissues, they can reduce plaque buildup in arteries while avoiding unintended effects. Prior animal studies have …

Pharmaceutical companies once considered a protein called p38 a very attractive target for treating rheumatoid arthritis. Arthritis patients usually have elevated activity of this inflammation-producing protein, and in lab studies p38 inhibitors appeared to soothe inflammation. However, these drugs failed in several clinical trials. A new study from MIT sheds …

SAN FRANCISCO: The group overseeing Internet addresses is scrambling to balance the privacy of website owners and the right to know who is behind online pages. The nonprofit Internet Corporation for Assigned Names and Numbers (ICANN) began a weeklong meeting Monday focused on the fate of the public Whois database, …