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A tiny RNA molecule plays a big role in the development of two diseases affecting billions of people worldwide: heart disease and obesity. Yale researchers have found that by disrupting this microRNA in key tissues, they can reduce plaque buildup in arteries while avoiding unintended effects. Prior animal studies have …

Pharmaceutical companies once considered a protein called p38 a very attractive target for treating rheumatoid arthritis. Arthritis patients usually have elevated activity of this inflammation-producing protein, and in lab studies p38 inhibitors appeared to soothe inflammation. However, these drugs failed in several clinical trials. A new study from MIT sheds …

SAN FRANCISCO: The group overseeing Internet addresses is scrambling to balance the privacy of website owners and the right to know who is behind online pages. The nonprofit Internet Corporation for Assigned Names and Numbers (ICANN) began a weeklong meeting Monday focused on the fate of the public Whois database, …

MUMBAI: The Kapoor sisters made their appearance together at the 17th India Today Conclave 2018. Kareena Kapoor and Karisma Kapoor spoke about almost everything, all the way from film to family and from nepotism to feminism. One of the most profound moments of the night was when the sisters met …

Music director and composer, Vipin Patwa, has backed Atif Aslam’s decision to not promote his song in upcoming film ‘Daas Dev’. Previously, the Pakistani sensation had refused to promote his song Sehmi Hai Dhadkan after Indian politician Babul Surpiyo made a vocal declarance of continuing the ban on Pakistani artists …

Malayalam actor Priya Prakash Varrier, who became an overnight sensation recently after her song went viral, has been reported to make her Bollywood debut opposite Ranveer Singh. According to a report by Deccan Chronicle, film-maker Rohit Shetty plans to cast Priya opposite Ranveer in his upcoming film, Simbaa, which is …

Hubert de Givenchy, the aristocratic French fashion designer famous for the “little black dress” and styling Audrey Hepburn and Jackie Kennedy, has died aged 91, his partner said Monday. Givenchy set the template for ladylike chic in the 1950s and 1960s, dressing everyone from Princess Grace of Monaco to Jane …

Pakistan’s Mixed Martial Arts (MMA) prospect Mehmosh Raza is up and ready for the biggest fight of his career against Ukrainian fighter Igor Grytskiv at China’s Rebel Fighting Championship on April 29. Mehmosh, who goes by the nickname of ‘The Renegade’, has made a swift rise over the past few …

PORT ELIZABETH: Fast bowler Kagiso Rabada took 11 wickets in the match but may yet turn from hero to villain as South Africa beat Australia by six wickets in the second Test on Monday to level the four-match series. South Africa made heavy work of reaching their modest target before …

DUBAI: In one of the most thrilling and finest match of the Pakistan Super League III, Lahore Qalandars outplayed Karachi Kings in a Super Over at Dubai International Stadium here on Sunday night. Karachi thus missed the chance to become the first team to qualify for the playoffs after losing …